The virtual international stroke trials archive
Identifieur interne : 009280 ( Main/Exploration ); précédent : 009279; suivant : 009281The virtual international stroke trials archive
Auteurs : Myzoon Ali [Royaume-Uni] ; Philip M. W. Bath [Royaume-Uni] ; John Curram [Royaume-Uni] ; Stephen M. Davis [Australie] ; Hans-Christoph Diener [Allemagne] ; Geoffrey A. Donnan [Australie] ; Marc Fisher [États-Unis] ; Barbara A. Gregson [Royaume-Uni] ; James Grotta [États-Unis] ; Werner Hacke [Allemagne] ; Michael G. Hennerici [Allemagne] ; Marc Hommel [France] ; Markku Kaste [Finlande] ; John R. Marler [États-Unis] ; Ralph L. Sacco [États-Unis] ; Philip Teal [Canada] ; Nils-Gunnar Wahlgren [Suède] ; Steven Warach [États-Unis] ; Christopher J. Weir [Royaume-Uni] ; Kennedy R. Lees [Royaume-Uni]Source :
- Stroke : (1970) [ 0039-2499 ] ; 2007.
Descripteurs français
English descriptors
Abstract
Background and Purpose-Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for reliable data on which to plan future clinical trials. The Virtual International Stroke Trials Archive aims to aid the planning of clinical trials by collating and providing access to a rich resource of patient data to perform exploratory analyses. Methods-Data were contributed by the principal investigators of numerous trials from the past 16 years. These data have been centrally collated and are available for anonymized analysis and hypothesis testing. Results-Currently, the Virtual International Stroke Trials Archive contains 21 trials. There are data on >15 000 patients with both ischemic and hemorrhagic stroke. Ages range between 18 and 103 years, with a mean age of 69±12 years. Outcome measures include the Barthel Index, Scandinavian Stroke Scale, National Institutes of Health Stroke Scale, Orgogozo Scale, and modified Rankin Scale. Medical history and onset-to-treatment time are readily available, and computed tomography lesion data are available for selected trials. Conclusions-This resource has the potential to influence clinical trial design and implementation through data analyses that inform planning.
Affiliations:
- Allemagne, Australie, Canada, Finlande, France, Royaume-Uni, Suède, États-Unis
- Angleterre, Auvergne-Rhône-Alpes, Bade-Wurtemberg, District de Karlsruhe, Nottinghamshire, Rhône-Alpes, Svealand, Uusimaa, Victoria (État), État de New York
- Grenoble, Heidelberg, Helsinki, Melbourne, New York, Nottingham, Stockholm
- Université Columbia, Université d'Helsinki, Université de Melbourne, Université de Nottingham
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 003B91
- to stream PascalFrancis, to step Curation: 002497
- to stream PascalFrancis, to step Checkpoint: 003546
- to stream Main, to step Merge: 009C58
- to stream Main, to step Curation: 009280
Le document en format XML
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Donnan</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Department of Neurology, University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>6 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Fisher, Marc" sort="Fisher, Marc" uniqKey="Fisher M" first="Marc" last="Fisher">Marc Fisher</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Neurology, University of Massachusetts Medical School</s1><s2>Worcester, Mass</s2><s3>USA</s3><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Worcester, Mass</wicri:noRegion></affiliation></author><author><name sortKey="Gregson, Barbara A" sort="Gregson, Barbara A" uniqKey="Gregson B" first="Barbara A." last="Gregson">Barbara A. Gregson</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Neurosurgery, Newcastle University, Newcastle General Hospital</s1><s2>Newcastle</s2><s3>GBR</s3><sZ>8 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle</wicri:noRegion></affiliation></author><author><name sortKey="Grotta, James" sort="Grotta, James" uniqKey="Grotta J" first="James" last="Grotta">James Grotta</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Neurology, University of Texas at Houston Medical School</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Houston, Tex</wicri:noRegion></affiliation></author><author><name sortKey="Hacke, Werner" sort="Hacke, Werner" uniqKey="Hacke W" first="Werner" last="Hacke">Werner Hacke</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Department of Neurology, University of Heidelberg</s1><s2>Heidelberg</s2><s3>DEU</s3><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Hennerici, Michael G" sort="Hennerici, Michael G" uniqKey="Hennerici M" first="Michael G." last="Hennerici">Michael G. Hennerici</name><affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Neurology, Universitätsklinikum Mannheim, University of Heidelberg</s1><s2>Heidelberg</s2><s3>DEU</s3><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Hommel, Marc" sort="Hommel, Marc" uniqKey="Hommel M" first="Marc" last="Hommel">Marc Hommel</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Joseph Fourier University</s1><s2>Grenoble</s2><s3>FRA</s3><sZ>12 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Kaste, Markku" sort="Kaste, Markku" uniqKey="Kaste M" first="Markku" last="Kaste">Markku Kaste</name><affiliation wicri:level="4"><inist:fA14 i1="13"><s1>Department of Neurology, Helsinki University Central Hospital, University of Helsinki</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>13 aut.</sZ></inist:fA14><country>Finlande</country><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName><orgName type="university">Université d'Helsinki</orgName></affiliation></author><author><name sortKey="Marler, John R" sort="Marler, John R" uniqKey="Marler J" first="John R." last="Marler">John R. Marler</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>National Institute of Neurological Disorders and Stroke</s1><s2>Bethesda, Md</s2><s3>USA</s3><sZ>14 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Institute of Neurological Disorders and Stroke</wicri:noRegion></affiliation></author><author><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L." last="Sacco">Ralph L. Sacco</name><affiliation wicri:level="4"><inist:fA14 i1="15"><s1>Departments of Neurology and Epidemiology, Columbia University</s1><s2>New York, NY</s2><s3>USA</s3><sZ>15 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Teal, Philip" sort="Teal, Philip" uniqKey="Teal P" first="Philip" last="Teal">Philip Teal</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>University of British Columbia</s1><s2>Vancouver</s2><s3>CAN</s3><sZ>16 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>University of British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Wahlgren, Nils Gunnar" sort="Wahlgren, Nils Gunnar" uniqKey="Wahlgren N" first="Nils-Gunnar" last="Wahlgren">Nils-Gunnar Wahlgren</name><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Karolinska Hospital</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>17 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Warach, Steven" sort="Warach, Steven" uniqKey="Warach S" first="Steven" last="Warach">Steven Warach</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>National Institute of Neurological Disorders and Stroke</s1><s2>Bethesda, Md</s2><s3>USA</s3><sZ>14 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Institute of Neurological Disorders and Stroke</wicri:noRegion></affiliation></author><author><name sortKey="Weir, Christopher J" sort="Weir, Christopher J" uniqKey="Weir C" first="Christopher J." last="Weir">Christopher J. Weir</name><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Robertson Centre for Biostatistics</s1><s2>Glasgow</s2><s3>GBR</s3><sZ>19 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Robertson Centre for Biostatistics</wicri:noRegion></affiliation></author><author><name sortKey="Lees, Kennedy R" sort="Lees, Kennedy R" uniqKey="Lees K" first="Kennedy R." last="Lees">Kennedy R. Lees</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Gardiner Institute, Western Infirmary</s1><s2>Glasgow</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Glasgow</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0283046</idno><date when="2007">2007</date><idno type="stanalyst">PASCAL 07-0283046 INIST</idno><idno type="RBID">Pascal:07-0283046</idno><idno type="wicri:Area/PascalFrancis/Corpus">003B91</idno><idno type="wicri:Area/PascalFrancis/Curation">002497</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">003546</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">003546</idno><idno type="wicri:doubleKey">0039-2499:2007:Ali M:the:virtual:international</idno><idno type="wicri:Area/Main/Merge">009C58</idno><idno type="wicri:Area/Main/Curation">009280</idno><idno type="wicri:Area/Main/Exploration">009280</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">The virtual international stroke trials archive</title><author><name sortKey="Ali, Myzoon" sort="Ali, Myzoon" uniqKey="Ali M" first="Myzoon" last="Ali">Myzoon Ali</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>University Department of Medicine and Therapeutics, Gardiner Institute, Western Infirmary</s1><s2>Glasgow</s2><s3>GBR</s3><sZ>1 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Glasgow</wicri:noRegion></affiliation></author><author><name sortKey="Bath, Philip M W" sort="Bath, Philip M W" uniqKey="Bath P" first="Philip M. W." last="Bath">Philip M. W. Bath</name><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Institute of Neuroscience, University of Nottingham</s1><s2>Nottingham</s2><s3>GBR</s3><sZ>2 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName><orgName type="university">Université de Nottingham</orgName></affiliation></author><author><name sortKey="Curram, John" sort="Curram, John" uniqKey="Curram J" first="John" last="Curram">John Curram</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Bayer Plc</s1><s2>Newbury, Berkshire</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Bayer Plc</wicri:noRegion></affiliation></author><author><name sortKey="Davis, Stephen M" sort="Davis, Stephen M" uniqKey="Davis S" first="Stephen M." last="Davis">Stephen M. Davis</name><affiliation wicri:level="4"><inist:fA14 i1="04"><s1>Department of Neurology, Royal Melbourne Hospital, University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>4 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Diener, Hans Christoph" sort="Diener, Hans Christoph" uniqKey="Diener H" first="Hans-Christoph" last="Diener">Hans-Christoph Diener</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Neurology, University Duisburg-Essen</s1><s2>Essen</s2><s3>DEU</s3><sZ>5 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Donnan, Geoffrey A" sort="Donnan, Geoffrey A" uniqKey="Donnan G" first="Geoffrey A." last="Donnan">Geoffrey A. Donnan</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Department of Neurology, University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>6 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Fisher, Marc" sort="Fisher, Marc" uniqKey="Fisher M" first="Marc" last="Fisher">Marc Fisher</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Neurology, University of Massachusetts Medical School</s1><s2>Worcester, Mass</s2><s3>USA</s3><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Worcester, Mass</wicri:noRegion></affiliation></author><author><name sortKey="Gregson, Barbara A" sort="Gregson, Barbara A" uniqKey="Gregson B" first="Barbara A." last="Gregson">Barbara A. Gregson</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Neurosurgery, Newcastle University, Newcastle General Hospital</s1><s2>Newcastle</s2><s3>GBR</s3><sZ>8 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle</wicri:noRegion></affiliation></author><author><name sortKey="Grotta, James" sort="Grotta, James" uniqKey="Grotta J" first="James" last="Grotta">James Grotta</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Neurology, University of Texas at Houston Medical School</s1><s2>Houston, Tex</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Houston, Tex</wicri:noRegion></affiliation></author><author><name sortKey="Hacke, Werner" sort="Hacke, Werner" uniqKey="Hacke W" first="Werner" last="Hacke">Werner Hacke</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Department of Neurology, University of Heidelberg</s1><s2>Heidelberg</s2><s3>DEU</s3><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Hennerici, Michael G" sort="Hennerici, Michael G" uniqKey="Hennerici M" first="Michael G." last="Hennerici">Michael G. Hennerici</name><affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Neurology, Universitätsklinikum Mannheim, University of Heidelberg</s1><s2>Heidelberg</s2><s3>DEU</s3><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Hommel, Marc" sort="Hommel, Marc" uniqKey="Hommel M" first="Marc" last="Hommel">Marc Hommel</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Joseph Fourier University</s1><s2>Grenoble</s2><s3>FRA</s3><sZ>12 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Kaste, Markku" sort="Kaste, Markku" uniqKey="Kaste M" first="Markku" last="Kaste">Markku Kaste</name><affiliation wicri:level="4"><inist:fA14 i1="13"><s1>Department of Neurology, Helsinki University Central Hospital, University of Helsinki</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>13 aut.</sZ></inist:fA14><country>Finlande</country><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName><orgName type="university">Université d'Helsinki</orgName></affiliation></author><author><name sortKey="Marler, John R" sort="Marler, John R" uniqKey="Marler J" first="John R." last="Marler">John R. Marler</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>National Institute of Neurological Disorders and Stroke</s1><s2>Bethesda, Md</s2><s3>USA</s3><sZ>14 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Institute of Neurological Disorders and Stroke</wicri:noRegion></affiliation></author><author><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L." last="Sacco">Ralph L. Sacco</name><affiliation wicri:level="4"><inist:fA14 i1="15"><s1>Departments of Neurology and Epidemiology, Columbia University</s1><s2>New York, NY</s2><s3>USA</s3><sZ>15 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Teal, Philip" sort="Teal, Philip" uniqKey="Teal P" first="Philip" last="Teal">Philip Teal</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>University of British Columbia</s1><s2>Vancouver</s2><s3>CAN</s3><sZ>16 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>University of British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Wahlgren, Nils Gunnar" sort="Wahlgren, Nils Gunnar" uniqKey="Wahlgren N" first="Nils-Gunnar" last="Wahlgren">Nils-Gunnar Wahlgren</name><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Karolinska Hospital</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>17 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Warach, Steven" sort="Warach, Steven" uniqKey="Warach S" first="Steven" last="Warach">Steven Warach</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>National Institute of Neurological Disorders and Stroke</s1><s2>Bethesda, Md</s2><s3>USA</s3><sZ>14 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Institute of Neurological Disorders and Stroke</wicri:noRegion></affiliation></author><author><name sortKey="Weir, Christopher J" sort="Weir, Christopher J" uniqKey="Weir C" first="Christopher J." last="Weir">Christopher J. Weir</name><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Robertson Centre for Biostatistics</s1><s2>Glasgow</s2><s3>GBR</s3><sZ>19 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Robertson Centre for Biostatistics</wicri:noRegion></affiliation></author><author><name sortKey="Lees, Kennedy R" sort="Lees, Kennedy R" uniqKey="Lees K" first="Kennedy R." last="Lees">Kennedy R. Lees</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Gardiner Institute, Western Infirmary</s1><s2>Glasgow</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Glasgow</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Stroke : (1970)</title><title level="j" type="abbreviated">Stroke : (1970)</title><idno type="ISSN">0039-2499</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Stroke : (1970)</title><title level="j" type="abbreviated">Stroke : (1970)</title><idno type="ISSN">0039-2499</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cerebrovascular disease</term><term>Nervous system diseases</term><term>Stroke</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Cérébrovasculaire pathologie</term><term>Accident cérébrovasculaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background and Purpose-Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for reliable data on which to plan future clinical trials. The Virtual International Stroke Trials Archive aims to aid the planning of clinical trials by collating and providing access to a rich resource of patient data to perform exploratory analyses. Methods-Data were contributed by the principal investigators of numerous trials from the past 16 years. These data have been centrally collated and are available for anonymized analysis and hypothesis testing. Results-Currently, the Virtual International Stroke Trials Archive contains 21 trials. There are data on >15 000 patients with both ischemic and hemorrhagic stroke. Ages range between 18 and 103 years, with a mean age of 69±12 years. Outcome measures include the Barthel Index, Scandinavian Stroke Scale, National Institutes of Health Stroke Scale, Orgogozo Scale, and modified Rankin Scale. Medical history and onset-to-treatment time are readily available, and computed tomography lesion data are available for selected trials. Conclusions-This resource has the potential to influence clinical trial design and implementation through data analyses that inform planning.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>Finlande</li><li>France</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>District de Karlsruhe</li><li>Nottinghamshire</li><li>Rhône-Alpes</li><li>Svealand</li><li>Uusimaa</li><li>Victoria (État)</li><li>État de New York</li></region><settlement><li>Grenoble</li><li>Heidelberg</li><li>Helsinki</li><li>Melbourne</li><li>New York</li><li>Nottingham</li><li>Stockholm</li></settlement><orgName><li>Université Columbia</li><li>Université d'Helsinki</li><li>Université de Melbourne</li><li>Université de Nottingham</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Ali, Myzoon" sort="Ali, Myzoon" uniqKey="Ali M" first="Myzoon" last="Ali">Myzoon Ali</name></noRegion><name sortKey="Bath, Philip M W" sort="Bath, Philip M W" uniqKey="Bath P" first="Philip M. W." last="Bath">Philip M. W. Bath</name><name sortKey="Curram, John" sort="Curram, John" uniqKey="Curram J" first="John" last="Curram">John Curram</name><name sortKey="Gregson, Barbara A" sort="Gregson, Barbara A" uniqKey="Gregson B" first="Barbara A." last="Gregson">Barbara A. Gregson</name><name sortKey="Lees, Kennedy R" sort="Lees, Kennedy R" uniqKey="Lees K" first="Kennedy R." last="Lees">Kennedy R. Lees</name><name sortKey="Weir, Christopher J" sort="Weir, Christopher J" uniqKey="Weir C" first="Christopher J." last="Weir">Christopher J. Weir</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Davis, Stephen M" sort="Davis, Stephen M" uniqKey="Davis S" first="Stephen M." last="Davis">Stephen M. Davis</name></region><name sortKey="Donnan, Geoffrey A" sort="Donnan, Geoffrey A" uniqKey="Donnan G" first="Geoffrey A." last="Donnan">Geoffrey A. Donnan</name></country><country name="Allemagne"><noRegion><name sortKey="Diener, Hans Christoph" sort="Diener, Hans Christoph" uniqKey="Diener H" first="Hans-Christoph" last="Diener">Hans-Christoph Diener</name></noRegion><name sortKey="Hacke, Werner" sort="Hacke, Werner" uniqKey="Hacke W" first="Werner" last="Hacke">Werner Hacke</name><name sortKey="Hennerici, Michael G" sort="Hennerici, Michael G" uniqKey="Hennerici M" first="Michael G." last="Hennerici">Michael G. Hennerici</name></country><country name="États-Unis"><noRegion><name sortKey="Fisher, Marc" sort="Fisher, Marc" uniqKey="Fisher M" first="Marc" last="Fisher">Marc Fisher</name></noRegion><name sortKey="Grotta, James" sort="Grotta, James" uniqKey="Grotta J" first="James" last="Grotta">James Grotta</name><name sortKey="Marler, John R" sort="Marler, John R" uniqKey="Marler J" first="John R." last="Marler">John R. Marler</name><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L." last="Sacco">Ralph L. Sacco</name><name sortKey="Warach, Steven" sort="Warach, Steven" uniqKey="Warach S" first="Steven" last="Warach">Steven Warach</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Hommel, Marc" sort="Hommel, Marc" uniqKey="Hommel M" first="Marc" last="Hommel">Marc Hommel</name></region></country><country name="Finlande"><region name="Uusimaa"><name sortKey="Kaste, Markku" sort="Kaste, Markku" uniqKey="Kaste M" first="Markku" last="Kaste">Markku Kaste</name></region></country><country name="Canada"><noRegion><name sortKey="Teal, Philip" sort="Teal, Philip" uniqKey="Teal P" first="Philip" last="Teal">Philip Teal</name></noRegion></country><country name="Suède"><region name="Svealand"><name sortKey="Wahlgren, Nils Gunnar" sort="Wahlgren, Nils Gunnar" uniqKey="Wahlgren N" first="Nils-Gunnar" last="Wahlgren">Nils-Gunnar Wahlgren</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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